morphine 6-dehydrogenase EC#: 1.1.1.218; ChemWhat Code: 1373295

Product Name morphine 6-dehydrogenase
Example Structure Example Structure of morphine 6-dehydrogenase EC#: 1.1.1.218
Synonyms AKR1C34, M6DH, More, morphine 6-dehydrogenase, morphine-6-dehydrogenase, naloxone reductase
EC Number 1.1.1.218
CAS Registry Number 106640-77-1;97002-71-6
Comments Also acts on some other alkaloids, including codeine, normorphine and ethylmorphine, but only very slowly on 7,8-saturated derivatives such as dihydromorphine and dihydrocodeine. In the reverse direction, also reduces naloxone to the 6¦Á-hydroxy analogue. Activated by 2-mercaptoethanol.
Cofactor
History
Reactions Morphine + NAD(P)(+) = morphinone + NAD(P)H.

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