myosin-heavy-chain kinase EC#: 2.7.11.7; ChemWhat Code: 1379005
| Product Name | myosin-heavy-chain kinase |
| Example Structure |  |
| Synonyms | A-CAT, kinase (phosphorylating), myosin heavy chain, MHCK, MHCK A, MHCK B, MHCK-A, MHCK-B, MIHC kinase, MIHCK, More, myosin heavy chain kinase, myosin heavy chain kinase A, myosin heavy chain kinase B, myosin heavy chain kinase C, myosin I heavy-chain kinase, myosin II heavy chain kinase, myosin II heavy chain kinase A, myosin II heavy chain kinase B, myosin II heavy chain kinases A, myosin II heavy chain kinases B, myosin II heavy-chain kinase, myosin-II heavy chain kinase A |
| EC Number | 2.7.11.7 |
| CAS Registry Number | 64763-54-8 |
| Comments | The enzyme from?Dictyostelium?sp. (slime moulds) brings about phosphorylation of the heavy chains of?Dictyostelium?myosin, inhibiting the actin-activated ATPase activity of the myosin. One threonine residue in each heavy chain acts as acceptor. While the enzyme from some species is activated by actin, in other cases Ca2+/calmodulin are required for activity. |
| Cofactor | |
| History | |
| Reactions | Atp + [myosin heavy-chain] = adp + [myosin heavy-chain] phosphate. |
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