O-phospho-L-seryl-tRNASec:L-selenocysteinyl-tRNA synthase EC#: 2.9.1.2; ChemWhat Code: 1379173

Product Name O-phospho-L-seryl-tRNASec:L-selenocysteinyl-tRNA synthase
Example Structure Example Structure of O-phospho-L-seryl-tRNASec:L-selenocysteinyl-tRNA synthase EC#: 2.9.1.2
Synonyms MMPSepSecS, O-phosphoserine tRNA: selenocysteine synthase, O-phosphoseryl-tRNA:selenocysteinyl-tRNA synthase, SelA, Selenocysteinyl-tRNA synthase, Sep tRNA: Sec synthase, SepSecS, SLA/LP
EC Number 2.9.1.2
CAS Registry Number
Comments A pyridoxal-phosphate protein [4]. In archaea and eukarya selenocysteine formation is achieved by a two-step process: EC?2.7.1.164?(O-phosphoseryl-tRNASec?kinase) phosphorylates the endogenous?L-seryl-tRNASec?to?O-phospho-L-seryl-tRNASec, and then this misacylated amino acid-tRNA species is converted to?L-selenocysteinyl-tRNASec?by Sep-tRNA:Sec-tRNA synthase.
Cofactor pyridoxal 5′-phosphate
History
Reactions O-phospho-L-seryl-tRNA(Sec) + selenophosphate + H(2)O = L-selenocysteinyl-tRNA(Sec) + 2 phosphate.

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