petromyzonol sulfotransferase EC#: 2.8.2.31; ChemWhat Code: 1379117

Product Name petromyzonol sulfotransferase
Example Structure Example Structure of petromyzonol sulfotransferase EC#: 2.8.2.31
Synonyms PZ-SULT
EC Number 2.8.2.31
CAS Registry Number
Comments The enzyme from the lamprey?Petromyzon marinus?can also use the corresponding 3-ketone as a substrate. It is stereoselective (5¦Á-cholane) and regioselective, exhibiting a preference for an hydroxy group at C-24. The enzyme is inactive when allocholic acid, which has a carboxy group at C-24, is used as a substrate.
Cofactor
History
Reactions 3′-phosphoadenylyl sulfate + 5-alpha-cholan-3-alpha,7-alpha,12-alpha,24- tetrol = adenosine 3′,5′-bisphosphate + 5-alpha-cholan-3-alpha,7- alpha,12-alpha-triol 24-sulfate.

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