phosphogluconate dehydrogenase (NADP+-dependent, decarboxylating) EC#: 1.1.1.44; ChemWhat Code: 1373025
| Product Name | phosphogluconate dehydrogenase (NADP+-dependent, decarboxylating) |
| Example Structure |  |
| Synonyms | 6-GPD, 6-P-gluconate dehydrogenase, 6-Pgd, 6-PGDH, 6-PGDHase, 6-phospho-D-gluconate dehydrogenase, 6-phospho-D-gluconate-NADP+ oxidoreductase, decarboxylating, 6-phosphogluconate dehydrogenase, 6-phosphogluconate dehydrogenase (decarboxylating), 6-phosphogluconate dehydrogenase Gnd1, 6-phosphogluconate dehydrogenase, decarboxylating, 6-phosphogluconate-dehydrogenase, 6-phosphogluconate:NADP oxidoreductase, 6-phosphogluconic carboxylase, 6-phosphogluconic dehydrogenase, 6-phosphonogluconate dehydrogenase, 6PDH, 6PG DH, 6PGD, 6PGDH, 6PGDH/Gnd1, D-gluconate-6-phosphate dehydrogenase, gnd, GND1, GNTZII, LlPDH, Moth_1283, Os6PGDH2, p6PGDH, peroxisomal 6-phosphogluconate dehydrogenase, PGD1, PGD2, PGD3, phosphogluconic acid dehydrogenase, TM0438, YpjI |
| EC Number | 1.1.1.44 |
| CAS Registry Number | 9073-95-4 |
| Comments | The enzyme participates in the oxidative branch of the pentose phosphate pathway, whose main purpose is to produce NADPH and pentose for biosynthetic reactions. Highly specific for NADP+. cf. EC 1.1.1.343, phosphogluconate dehydrogenase (NAD+-dependent, decarboxylating). |
| Cofactor | |
| History | |
| Reactions | 6-phospho-D-gluconate + NADP(+) = D-ribulose 5-phosphate + CO(2) + Nadph. |
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