phosphonopyruvate decarboxylase EC#: 4.1.1.82; ChemWhat Code: 1381988

Product Name phosphonopyruvate decarboxylase
Example Structure Example Structure of phosphonopyruvate decarboxylase EC#: 4.1.1.82
Synonyms PnPy decarboxylase, Ppd, PPDC, Ppyr decarboxylase
EC Number 4.1.1.82
CAS Registry Number
Comments The enzyme catalyses a step in the biosynthetic pathway of 2-aminoethylphosphonate, a component of the capsular polysaccharide complex of?Bacteroides fragilis. Requires thiamine diphosphate and Mg2+?as cofactors. The enzyme is activated by the divalent cations Mg2+, Ca2+?and Mn2+. Pyruvate and sulfopyruvate can also act as substrates, but more slowly.
Cofactor thiamine diphosphate Mg2+
History
Reactions 3-phosphonopyruvate = 2-phosphonoacetaldehyde + CO(2).

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