phosphopantothenate-cysteine ligase (CTP) EC#: 6.3.2.5; ChemWhat Code: 1383719
| Product Name | phosphopantothenate-cysteine ligase (CTP) |
| Example Structure |  |
| Synonyms | 4¡¯-phosphopantothenoylcysteine synthetase, CoaB, CoaBC, coupling enzyme, Dfp, pantothenate 4?-phosphate:L-cysteine ligase, phosphopantothenate-cysteine ligase, phosphopantothenoyl-cysteine ligase, phosphopantothenoylcysteine synthetase, PPC synthase, PPC synthetase, PPC-S, PPCS, synthetase, phosphopantothenoylcysteine |
| EC Number | 6.3.2.5 |
| CAS Registry Number | 9023-50-1 |
| Comments | A key enzyme in the production of coenzyme A. The bacterial enzyme requires CTP, in contrast to the eukaryotic enzyme, EC?6.3.2.51, which requires ATP. Cysteine can be replaced by some of its derivatives. |
| Cofactor | |
| History | |
| Reactions | Ctp + (R)-4′-phosphopantothenate + L-cysteine = cmp + diphosphate + N-((R)-4′-phosphopantothenoyl)-L-cysteine. |
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