precorrin-6B C5,15-methyltransferase (decarboxylating) EC#: 2.1.1.132; ChemWhat Code: 1376324

Product Name precorrin-6B C5,15-methyltransferase (decarboxylating)
Example Structure Example Structure of precorrin-6B C5,15-methyltransferase (decarboxylating) EC#: 2.1.1.132
Synonyms CobL, GenBank L12005-derived protein, Genbank L12006-derived protein, GenBank U67594-derived protein GI 1500413, Gene cbiE precorrin 6y methylase, Gene cbiT precorrin methylase, Methyltransferase precorrin 6y (Salmonella typhimurium strain LT2 gene cbiE), methyltransferase, precorrin 6y, Methyltransferase, precorrin 6y (Methanococcus jannaschii), Methyltransferase, precorrin 6y (Salmonella typhimurium strain LT2 gene cbiT), Precorrhin-6y methyltransferase, Precorrin-6 methyltransferase, Precorrin-6Y methylase, precorrin-6y methyltransferase, precorrin-8w decarboxylase, Protein (Salmonella typhimurium clone pJO gene cbiE reduced), Protein (Salmonella typhimurium clone pJO26 gene cbiT reduced)
EC Number 2.1.1.132
CAS Registry Number 162995-22-4
Comments The enzyme, which participates in the aerobic adenosylcobalamin biosynthesis pathway, has S-adenosyl-L-methionine-dependent methyltransferase and decarboxylase activities. The enzyme is a fusion protein with two active sites; one catalyses the methylation at C15 and the decarboxylation, while the other catalyses the methylation at C5.
Cofactor
History
Reactions 2 S-adenosyl-L-methionine + precorrin-6B = 2 S-adenosyl-L-homocysteine + precorrin-8X + CO(2).

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