prostaglandin-E synthase EC#: 5.3.99.3; ChemWhat Code: 1383295

Product Name prostaglandin-E synthase
Example Structure Example Structure of prostaglandin-E synthase EC#: 5.3.99.3
Synonyms CPGES, cPGES/p23, cytosolic prostaglandin E synthase, cytosolic prostaglandin E(2) synthase, cytosolic prostaglandin E(2) synthase-2, endoperoxide isomerase, Isomerase, prostaglandin R2 E-, membrane-associated PGE2 synthase, membrane-associated prostaglandin E synthase-2, membrane-associated prostaglandin E(2) synthase-1, membrane-associated prostaglandin E(2) synthase-2, microsomal PG synthase-1, microsomal PGE synthase-1, microsomal PGE2 synthase, microsomal PGE2 synthase-1, microsomal prostaglandin E synthase, microsomal prostaglandin E synthase 1, microsomal prostaglandin E synthase type 1, microsomal prostaglandin E synthase type 2, microsomal prostaglandin E synthase type-2, microsomal prostaglandin E synthase-1, microsomal prostaglandin E synthase-2, microsomal prostaglandin E(2) synthase-1, microsomal prostaglandin E(2) synthase-2, microsomal prostaglandin E2 synthase 1, microsomal prostaglandin E2 synthase type 1, microsomal prostaglandin E2 synthase-1, microsomal prostaglandin synthase-1, microsomal prostaglandin-E synthase-1, mPGE synthase-2, mPGES, mPGES-1, mPGES-2, MPGES1, MPGES2, p23, PGE, PGE isomerase, PGE synthase, PGE synthase-1, PGE2, PGE2 isomerase, PGE2 synthase, PGE2-synthase, PGES, PGES-1, PGES-2, PGH-PGE isomerase, PGH2/PGE2 isomerase, prostagandin-E synthetase, Prostaglandin E synthase, prostaglandin E synthase 1, prostaglandin E synthase type 2, prostaglandin E synthase-1, prostaglandin E synthase-2, Prostaglandin E2 isomerase, prostaglandin E2 synthase, prostaglandin E2 synthase-1, prostaglandin E2 synthase-I, Prostaglandin endoperoxide E isomerase, Prostaglandin endoperoxide E2 isomerase, Prostaglandin endoperoxide-E isomerase, Prostaglandin H-E isomerase, Prostaglandin H-prostaglandin E isomerase, Prostaglandin R-prostaglandin E isomerase, prostaglandin synthase-1, prostaglandin-E synthase, Prostaglandin-H2 E-isomerase, PTGES
EC Number 5.3.99.3
CAS Registry Number 52227-79-9
Comments Brings about the opening of the epidioxy bridge. Requires glutathione.
Cofactor glutathione
History
Reactions (5Z,13E)-(15S)-9-alpha,11-alpha-epidioxy-15-hydroxyprosta-5,13-dienoate = (5Z,13E)-(15S)-11-alpha,15-dihydroxy-9-oxoprosta-5,13-dienoate.

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