prostaglandin-I synthase EC#: 5.3.99.4; ChemWhat Code: 1383297

Product Name prostaglandin-I synthase
Example Structure Example Structure of prostaglandin-I synthase EC#: 5.3.99.4
Synonyms Aortic cytochrom P450, CYP8A1, PGI synthase, PGI2 synthase, PGI2 synthetase, PGI2-S, PGIS, prostacyclin synthase, Prostacyclin synthetase, prostacyclin-synthase, prostacyclin/PGI2 synthase, Prostacycline synthetase, prostaglandin I synthase, Prostaglandin I2 synthase, Prostaglandin I2 synthetase, Ptgis, Synthetase, prostacyclin
EC Number 5.3.99.4
CAS Registry Number
Comments A cytochrome P-450 heme-thiolate enzyme. Converts prostaglandin H2?into prostaglandin I2?(prostacyclin).
Cofactor heme-thiolate
History
Reactions (5Z,13E)-(15S)-9-alpha,11-alpha-epidioxy-15-hydroxyprosta-5,13-dienoate = (5Z,13E)-(15S)-6,9-alpha-epoxy-11-alpha,15-dihydroxyprosta-5,13-dienoate.

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