protein N-terminal monomethyltransferase EC#: 2.1.1.299; ChemWhat Code: 1376577

Product Name protein N-terminal monomethyltransferase
Example Structure Example Structure of protein N-terminal monomethyltransferase EC#: 2.1.1.299
Synonyms METTL11B, N-terminal monomethylase, NRMT2
EC Number 2.1.1.299
CAS Registry Number
Comments This enzyme methylates the N-terminus of target proteins containing the N-terminal motif [Ala/Pro/Ser]-Pro-Lys after the initiator L-methionine is cleaved. In contrast to EC 2.1.1.244, protein N-terminal methyltransferase, the protein only adds one methyl group to the N-terminal.
Cofactor
History
Reactions S-adenosyl-L-methionine + N-terminal-(A,P,S)PK-[protein] = S-adenosyl-L- homocysteine + N-terminal-N-methyl-N-(A,P,S)PK-[protein].

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