protein-Npi-phosphohistidine-D-galactose phosphotransferase EC#: 2.7.1.204; ChemWhat Code: 1378609

Product Name protein-Npi-phosphohistidine-D-galactose phosphotransferase
Example Structure Example Structure of protein-Npi-phosphohistidine-D-galactose phosphotransferase EC#: 2.7.1.204
Synonyms D-galactose PTS permease, EIIGal, phosphotransferase system permease specific for galactose
EC Number 2.7.1.204
CAS Registry Number
Comments This enzyme is a component (known as enzyme II) of a phosphoenolpyruvate (PEP)-dependent, sugar transporting phosphotransferase system (PTS). The system, which is found only in prokaryotes, simultaneously transports its substrate from the periplasm or extracellular space into the cytoplasm and phosphorylates it. The phosphate donor, which is shared among the different systems, is a phospho-carrier protein of low molecular mass that has been phosphorylated by EC?2.7.3.9?(phosphoenolpyruvate¡ªprotein phosphotransferase). Enzyme II, on the other hand, is specific for a particular substrate, although in some cases alternative substrates can be transported with lower efficiency. The reaction involves a successive transfer of the phosphate group to several amino acids within the enzyme before the final transfer to the substrate.
Cofactor
History
Reactions [Protein]-N(pi)-phospho-L-histidine + D-galactose(Side 1) = [protein]-L- histidine + D-galactose 6-phosphate(Side 2).

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