protein-Npi-phosphohistidine-D-glucose phosphotransferase EC#: 2.7.1.199; ChemWhat Code: 1378601

Product Name protein-Npi-phosphohistidine-D-glucose phosphotransferase
Example Structure Example Structure of protein-Npi-phosphohistidine-D-glucose phosphotransferase EC#: 2.7.1.199
Synonyms D-glucose PTS permease, EIICBAGlc1, EIICBAGlc2, EIICBGlc, EIIGlc, enzyme II-BGlc, enzyme IICBGlc, enzyme IIGlc, glcA, glucose permease, glucose PTS permease, glucose transporter, glucose-permease, glucose-PTS transporter, glucose-specific carrier, glucose-specific enzyme I1, glucose-specific enzyme II, glucose-specific enzyme IICBA PTS component, glucose-specific permease, glucose-specific PTS enzyme II, glucose-specific PTS permease, glucose-specific transporter of phosphoenolpyruvate:carbohydrate phosphotransferase system, glucose-specific transporter of the phosphotransferase system, II-BGlc, IIAGlc, IIBCGlc, IIBGlc, IICBA Glc, IICBGlc, IIGlc, phosphoenolpyruvate-dependent glucose-phosphotransferase system, PtsG, ptsG-I
EC Number 2.7.1.199
CAS Registry Number
Comments This enzyme is a component (known as enzyme II) of a phosphoenolpyruvate (PEP)-dependent, sugar transporting phosphotransferase system (PTS). The system, which is found only in prokaryotes, simultaneously transports its substrate from the periplasm or extracellular space into the cytoplasm and phosphorylates it. The phosphate donor, which is shared among the different systems, is a phospho-carrier protein of low molecular mass that has been phosphorylated by EC?2.7.3.9?(phosphoenolpyruvate¡ªprotein phosphotransferase). Enzyme II, on the other hand, is specific for a particular substrate, although in some cases alternative substrates can be transported with lower efficiency. The reaction involves a successive transfer of the phosphate group to several amino acids within the enzyme before the final transfer to the substrate.
Cofactor
History
Reactions [Protein]-N(pi)-phospho-L-histidine + D-glucose(Side 1) = [protein]-L- histidine + D-glucose 6-phosphate(Side 2).

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