| Synonyms |
D-mannitol PTS permease, D-rnannitol-specific enzyme I1, EII mtl, EIIMtl, enzyme IImtl, EnzymeIImtl, IIAmtl, IIBmtl, IImtl, ma nnitol-specific enzyme II, mannitol enzyme I1, mannitol permease, mannitol specific enzyme II, mannitol-specific carrier, mannitol-specific EII, mannitol-specific enzyme I1, mannitol-specific enzyme II, mannitol-specific enzyme II of the phosphoenolpyruvate-dependent phosphotransferase system, mannitol-specific enzyme IImtl, mannitolspecific enzyme II of the phosphotransferase system, mtlA, mtlI, phosphoenolpyruvate-dependent mannitol-specific transport protein, phosphotransferase IIAmannitol |
| Comments |
This enzyme is a component (known as enzyme II) of a phosphoenolpyruvate (PEP)-dependent, sugar transporting phosphotransferase system (PTS). The system, which is found only in prokaryotes, simultaneously transports its substrate from the periplasm or extracellular space into the cytoplasm and phosphorylates it. The phosphate donor, which is shared among the different systems, is a phospho-carrier protein of low molecular mass that has been phosphorylated by EC?2.7.3.9?(phosphoenolpyruvate¡ªprotein phosphotransferase). Enzyme II, on the other hand, is specific for a particular substrate, although in some cases alternative substrates can be transported with lower efficiency. The reaction involves a successive transfer of the phosphate group to several amino acids within the enzyme before the final transfer to the substrate. |
