rhodopsin kinase EC#: 2.7.11.14; ChemWhat Code: 1379017

Product Name rhodopsin kinase
Example Structure Example Structure of rhodopsin kinase EC#: 2.7.11.14
Synonyms cone-specific kinase GRK7, G protein receptor kinase 1, G protein-coupled receptor kinase, G protein-coupled receptor kinase 1, G protein-coupled receptor kinase GRK7, G-protein coupled protein kinase 7a, G-protein coupled protein kinase 7b, G-protein coupled receptor kinase, G-protein coupled receptor kinase 1, G-protein receptor kinase, G-protein-coupled receptor kinase 1, GPCR kinase 1, GPRK1, GRK1, GRK7, kinase (phosphorylating), opsin, kinase (phosphorylating), rhodopsin, More, opsin kinase, rhodopsin kinase, RK, SQRK
EC Number 2.7.11.14
CAS Registry Number 54004-64-7
Comments Requires G-protein for activation and therefore belongs to the family of G-protein-dependent receptor kinases (GRKs). Acts on the bleached or activated form of rhodopsin; also phosphorylates the ¦Â-adrenergic receptor, but more slowly. Does not act on casein, histones or phosphvitin. Inhibited by Zn2+?and digitonin (cf. EC?2.7.11.15, ¦Â-adrenergic-receptor kinase and EC?2.7.11.16, G-protein-coupled receptor kinase).
Cofactor
History
Reactions Atp + [rhodopsin] = adp + [rhodopsin] phosphate.

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