(S)-nandinine synthase EC#: 1.14.19.73; ChemWhat Code: 1375838
Product Name | (S)-nandinine synthase |
Example Structure | |
Synonyms | (S)-stylopine synthase 2, CYP719A3 |
EC Number | 1.14.19.73 |
CAS Registry Number | |
Comments | A cytochrome P450 (heme-thiolate) enzyme found in plants. The enzyme catalyses an oxidative reaction that does not incorporate oxygen into the product. Forms the methylenedioxy bridge of the protoberberine alkaloid (S)-nandinine by the oxidative ring closure of adjacent phenolic and methoxy groups of (S)-scoulerine. cf. EC 1.14.19.65, (S)-cheilanthifoline synthase, which catalyses a similar reaction at the other side of the (S)-scoulerine molecule, forming (S)-cheilanthifoline. |
Cofactor | heme-thiolate |
History | |
Reactions |
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