(S)-nandinine synthase EC#: 1.14.19.73; ChemWhat Code: 1375838

Product Name (S)-nandinine synthase
Example Structure Example Structure of (S)-nandinine synthase EC#: 1.14.19.73
Synonyms (S)-stylopine synthase 2, CYP719A3
EC Number 1.14.19.73
CAS Registry Number
Comments A cytochrome P450 (heme-thiolate) enzyme found in plants. The enzyme catalyses an oxidative reaction that does not incorporate oxygen into the product. Forms the methylenedioxy bridge of the protoberberine alkaloid (S)-nandinine by the oxidative ring closure of adjacent phenolic and methoxy groups of (S)-scoulerine. cf. EC 1.14.19.65, (S)-cheilanthifoline synthase, which catalyses a similar reaction at the other side of the (S)-scoulerine molecule, forming (S)-cheilanthifoline.
Cofactor heme-thiolate
History
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