staphyloferrin A synthase EC#: 6.3.2.57; ChemWhat Code: 1383800
Product Name | staphyloferrin A synthase |
Example Structure | |
Synonyms | sfaBD, sfnaB |
EC Number | 6.3.2.57 |
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Comments | Requires Mg2+. The enzyme, characterized from the bacterium?Staphylococcus aureus, catalyses the last step in the biosynthesis of the siderophore staphyloferrin A. It belongs to a class of siderophore synthases known as type A nonribosomal peptide synthase-independent synthases (NIS). Type A NIS enzymes are responsible for the formation of amide or ester bonds between polyamines or amino alcohols and a prochiral carboxyl group of citrate. The enzyme forms a citrate adenylate intermediate prior to ligation. |
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