sulfur carrier protein ThiS adenylyltransferase EC#: 2.7.7.73; ChemWhat Code: 1378873
| Product Name | sulfur carrier protein ThiS adenylyltransferase |
| Example Structure |  |
| Synonyms | ThiF |
| EC Number | 2.7.7.73 |
| CAS Registry Number | |
| Comments | Binds Zn2+. The enzyme catalyses the adenylation of ThiS, a sulfur carrier protein involved in the biosynthesis of thiamine. The enzyme shows significant structural similarity to ubiquitin-activating enzyme [3,4]. In?Escherichia coli, but not in?Bacillus subtilis, the enzyme forms a cross link from Cys-184 to the ThiS carboxy terminus (the position that is also thiolated) via an acyldisulfide [2]. |
| Cofactor | Zn2+ |
| History | |
| Reactions | Atp + [ThiS] = diphosphate + adenylyl-[ThiS]. |
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