tRNA (adenine58-N1)-methyltransferase EC#: 2.1.1.220; ChemWhat Code: 1376461
| Product Name | tRNA (adenine58-N1)-methyltransferase |
| Example Structure |  |
| Synonyms | Gcd10p, Gcd10p-Gcd14p, Gcd10pyGcd14p complex, Gcd14p, m1A58 MTase, m1A58 tRNA methyltransferase, m1A58-methyltransferase, m1A58MTase, Rv2118c, Rv2118p, TRm61p, TRm6p, TrmI, tRNA (m1A58) methyltransferase, tRNA (m1A58) MTase, tRNA m1A58 methyltransferase |
| EC Number | 2.1.1.220 |
| CAS Registry Number | |
| Comments | The enzyme specifically methylates adenine58 in tRNA. The methylation of A58 is critical for maintaining the stability of initiator tRNAMet in yeast [3]. |
| Cofactor | |
| History | |
| Reactions | S-adenosyl-L-methionine + adenine(58) in tRNA = S-adenosyl-L-homocysteine + N(1)-methyladenine(58) in tRNA. |
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