tRNA pseudouridine38/39 synthase EC#: 5.4.99.45; ChemWhat Code: 1383440

Product Name tRNA pseudouridine38/39 synthase
Example Structure Example Structure of tRNA pseudouridine38/39 synthase EC#: 5.4.99.45
Synonyms Deg1, Deg1p, mPus3p, pseudouridine synthase 3, PUS3, PUS3/DEG1, Pus3p
EC Number 5.4.99.45
CAS Registry Number
Comments The enzyme from?Saccharomyces cerevisiae?is active only towards uridine38?and uridine39, and shows no activity with uridine40?(cf. EC?5.4.99.12, tRNA pseudouridine38-40?synthase) [1]. In vitro the enzyme from mouse is active on uridine39?and very slightly on uridine38?(human tRNALeu) [2].
Cofactor
History
Reactions tRNA uridine(38/39) = tRNA pseudouridine(38/39).

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