type III protein arginine methyltransferase EC#: 2.1.1.321; ChemWhat Code: 1376606
Product Name | type III protein arginine methyltransferase |
Example Structure | |
Synonyms | PRMT7, Q9NVM4 {UniProt} |
EC Number | 2.1.1.321 |
CAS Registry Number | |
Comments | Type III protein arginine methyltransferases catalyse the single methylation of one of the terminal nitrogen atoms of the guanidino group in an L-arginine residue within a protein. Unlike type I and type II protein arginine methyltransferases, which also catalyse this reaction, type III enzymes do not methylate the substrate any further. cf. EC 2.1.1.319, type I protein arginine methyltransferase, EC 2.1.1.320, type II protein arginine methyltransferase, and EC 2.1.1.322, type IV protein arginine methyltransferase. |
Cofactor | |
History | |
Reactions | S-adenosyl-L-methionine + [protein]-L-arginine = S-adenosyl-L- homocysteine + [protein]-N(omega)-methyl-L-arginine. |
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