U6 snRNA m6A methyltransferase EC#: 2.1.1.346; ChemWhat Code: 1376632
| Product Name | U6 snRNA m6A methyltransferase |
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| Synonyms | methyltransferase like protein 16, METTL16, N6-methyladenosine (m6A) methyltransferase |
| EC Number | 2.1.1.346 |
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| Comments | This enzyme, found in vertebrates, methylates a specific adenine in a hairpin structure of snRNA. The effects of the binding of the methyltransferase to its substrate is important for the regulation of the activity of an isoform of EC 2.5.1.6, methionine adenosyltransferase, that produces S-adenosyl-L-methionine [1,2]. The enzyme also binds (and maybe methylates) the lncRNAs XIST and MALAT1 as well as a number of pre-mRNAs at specific positions often found in the intronic regions [2]. |
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