UDP-N-acetylglucosamine-decaprenyl-phosphate N-acetylglucosaminephosphotransferase EC#: 2.7.8.35; ChemWhat Code: 1378968

Product Name UDP-N-acetylglucosamine-decaprenyl-phosphate N-acetylglucosaminephosphotransferase
Example Structure Example Structure of UDP-N-acetylglucosamine-decaprenyl-phosphate N-acetylglucosaminephosphotransferase EC#: 2.7.8.35
Synonyms decaprenyl-phosphate N-acetylglucosaminephosphotransferase, GlcNAc-1-phosphate transferase, MSMEG 4947, MSMEG_4947, N-acetylglucosamine-1-phosphate transferase, polyprenyl phosphate-GlcNAc-1-phosphate transferase, Rv1302, UDP-GlcNAc: undecaprenyl phosphate GlcNAc-1-phosphate transferase, UDP-GlcNAc:undecaprenyl phosphate GlcNAc-1-phosphate transferase, WecA, WecA transferase
EC Number 2.7.8.35
CAS Registry Number
Comments Isolated from?Mycobacterium tuberculosis?and?Mycobacterium smegmatis. This enzyme catalyses the synthesis of monotrans,octacis-decaprenyl-N-acetyl-¦Á-D-glucosaminyl diphosphate (mycobacterial lipid I), an essential lipid intermediate for the biosynthesis of various bacterial cell envelope components.?cf. EC?2.7.8.33, UDP-GlcNAc:undecaprenyl-phosphate GlcNAc-1-phosphate transferase.
Cofactor
History
Reactions UDP-N-acetyl-alpha-D-glucosamine + trans,octacis-decaprenyl phosphate = Ump + N-acetyl-alpha-D-glucosaminyl-diphospho-trans,octacis-decaprenol.

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