Synonyms |
MurD, murD2, UDP-MurNAc-L-Ala-D-Glu synthetase, UDP-MurNAc-L-Ala-L-Glu synthetase, UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-L-glutamate synthetase, UDP-N-acetylmuramyl-L-alanine:D-glutamate ligase, XOO_1320 |
Comments |
The enzyme, characterized from the bacterium?Xanthomonas oryzae, catalyses the ligation of a terminal?L-glutamate to UDP-N-acetyl-¦Á-D-muramoyl-L-alanine. The combined activity of this enzyme and EC?5.1.1.23, UDP-N-acetyl-¦Á-D-muramoyl-L-alanyl-L-glutamate epimerase, provides an alternative route for incorporating?D-glutamate into peptidoglycan, replacing the more common combination of EC?5.1.1.3, glutamate racemase, and EC?6.3.2.9, UDP-N-acetylmuramoyl-L-alanine¡ªD-glutamate ligase. |