UDP-N-acetylmuramoyl-L-alanyl-D-glutamate-L-lysine ligase EC#: 6.3.2.7; ChemWhat Code: 1383723
Product Name | UDP-N-acetylmuramoyl-L-alanyl-D-glutamate-L-lysine ligase |
Example Structure | |
Synonyms | MuE, MurE, Synthetase, uridine diphospho-N-acetylmuramoylalanyl-D-glutamyllysine, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate-lysine ligase, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate: L-lysine ligase, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate:L-lysine ligase, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate:meso-2,6-diaminopimelate ligase, UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysine synthetase, uridine 5′-diphospho-N-acetylmuramoyl L-alanyl-D-glutamate:lysine ligase, Uridine diphospho-N-acetylmuramoylalanyl-D-glutamyllysine synthetase |
EC Number | 6.3.2.7 |
CAS Registry Number | 9023-51-2 |
Comments | Involved in the synthesis of a cell-wall peptide. This enzyme adds lysine in some Gram-positive organisms; in others and in Gram-negative organisms EC?6.3.2.13?(UDP-N-acetylmuramoylalanyl-D-glutamate¡ª2,6-diaminopimelate ligase) adds 2,6-diaminopimelate instead. |
Cofactor | |
History | |
Reactions | Atp + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamate + L-lysine = Adp + phosphate + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-gamma-D- glutamyl-L-lysine. |
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