UMP kinase EC#: 2.7.4.22; ChemWhat Code: 1378713
| Product Name | UMP kinase |
| Example Structure |  |
| Synonyms | ATP:UMP phosphotransferase, HP0777 protein, More, pyrH, Rv2883c, SsUMPK, UMP kinase, UMP-kinase, UMPK, UMPKs, uridine monophosphate kinase, uridylate kinase, XC1936 |
| EC Number | 2.7.4.22 |
| CAS Registry Number | |
| Comments | This enzyme is strictly specific for UMP as substrate and is used by prokaryotes in the de novo synthesis of pyrimidines, in contrast to eukaryotes, which use the dual-specificity enzyme UMP/CMP kinase (EC?2.7.4.14) for the same purpose [2]. This enzyme is the subject of feedback regulation, being inhibited by UTP and activated by GTP [1]. |
| Cofactor | |
| History | |
| Reactions | Atp + ump = adp + udp. |
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